SCOTTSBURG, Ind. (AP): Authorities have arrested 10 people on drug charges alleging they distributed drugs that helped fuel the worst HIV outbreak in Indiana history.

The 10 people were arrested Friday after being indicted on charges that include conspiracy to distribute and distribution of a controlled substance.

Authorities say those arrested include a Scottsburg couple accused of orchestrating the movement of the prescription painkiller Opana and methamphetamine in the Scott County city of Austin.

U.S. Department of Justice spokesman Tim Horty said all 10 were due to make initial court appearances Friday afternoon.

State health officials say southeastern Indiana’s HIV outbreak has been driven by needle-sharing among people injecting a liquefied form of Opana. That outbreak includes 188 cases.

Nearly all have been in Scott County, about 30 miles north of Louisville, Kentucky.