EVANSILLE, Ind. (AP) – The Vanderburgh County Prosecutor's Office says arrest warrants have been issued for more than 50 people accused of participating in local meth-trafficking.

According to the office, 74 pounds of uncut methamphetamine worth more than $3.3 million have been seized throughout the course of a two-year investigation. Prosecutor Nicholas Hermann says investigators determined their efforts caused more than 134,300 single uses of meth to be taken off the market.

Hermann says the investigation focused on the Jimtown neighborhood of Evansville, located north of the Lloyd Expressway. He says he's confident the investigation put a dent in the short-term supply of crystal meth in the area.

The Evansville Courier & Press (http://bit.ly/1C3xS1t ) reports the investigation relied heavily on tips from residents. 

Twenty-one federal, state and local agencies participated in the investigation.